Why do I need this test?
Oesophageal cancer (Oesophageal Adenocarcinoma) is the seventh leading cause of cancer-related death and the eleventh most common cancer1.
Current screening methods (endoscopy with biopsy) are invasive and have not reduced the number of oesophageal cancer cases4, while misdiagnosis can lead to over or under-treatment5,6.
This new Oesophageal Health Test is a non-invasive, cost-effective blood test designed to rule out oesophageal adenocarcinoma with a high level of accuracy.
Recent research shows the test accurately rules out Esophageal Adenocarcinoma (EAC), with a specificity of 98.9%, an improvement on the 87% achieved by endoscopy. Based on disease prevalence, this converts to a 99.9% Negative Predictive Value (NPV), meaning you have a low likelihood of requiring unnecessary and costly procedures8.
What are the symptoms of oesophagael cancer?
Many people who have the early stages of oesophageal cancer do not have any symptoms, so it is often not picked up until the later stages.
When symptoms occur, they can include:
- pain or difficulty with swallowing or choking when you swallow
- getting food stuck in your throat or coming back up
- persistent heartburn or reflux
- pain in the upper part of your belly when you eat
- a persistent cough or hoarse voice.
Who should take this test?
The test is suitable for adults who have not previously been diagnosed with cancer and who have at least two risk factors for EAC (persistent heartburn or chronic acid reflux, age over 50 years, and overweight i.e. body mass index (BMI) > 25 kg/m2).
Is this test a reliable measure?
This non invasive blood test identifies 4 biomarkers that are linked with this type of cancer, then combines this with age, sex, and BMI (a calculation using your weight and height) data to calculate a risk score. Research has shown that it accurately detects oesophageal adenocarcinoma in 91.4% of cases.
What to expect with your results?
The Oesophageal Health Test algorithm works out a score indicating your likelihood of oesophageal cancer. The test results use a traffic light system to classify your risk.
- Green = low risk of oesophageal adenocarcinoma
- Amber = moderate risk of oesophageal adenocarcinoma
- Red = high risk of oesophageal adenocarcinoma
What happens after I get my result?
A green result will give you peace of mind. If your result is amber or high risk, your doctor will likely recommend further evaluation to confirm the diagnosis and guide treatment. This may include:
- Referral to a Specialist: You may be referred to a gastroenterologist for further assessment.
- Diagnostic Tests: Additional tests, such as an endoscopy and biopsy, may be conducted to confirm the presence of oesophageal cancer or pre-cancerous changes.
- Monitoring and Treatment Planning: Based on your results, your doctor may create a tailored plan, which could involve regular monitoring, lifestyle changes, or early treatment options to manage or reduce your risk.
Available from 17th Sept, 2025
Oesophageal Health Test
Oesophageal cancer is on the rise in Australia1. Your risk may be higher if you are over 50, overweight, or suffer from chronic reflux (GORD)2,3.
Diagnosis usually requires an invasive, costly endoscopy. The Oesophageal Health Test is a blood test designed to rule out Oesophageal Cancer.
For patients with persistent heartburn or chronic acid reflux
Rule out oesophageal adenocarcinoma (cancer)
Sample Type: Blood Test
Authorisation: Telehealth consult included
Results: 2 to 4 weeks from sample collection
How it works
1
Check if you are eligible
Answer a few quick questions about your health online. If you're eligible you can purchase a consultation.
2
Talk to a doctor over the phone
Book a telehealth consultation with a licensed doctor to approve your test request.
3
Provide your sample
Take your request form to a participating collection centre to have your blood samples taken.
4
Get answers in days
Once your results are ready, you’ll receive communication whether an online follow-up with your doctor (included in test cost) to review your results is necessary.
Disclaimer: The method employed for this test is pending accreditation and performed under a quality system aligned with ISO 15189:2022.
Risk-free Guarantee
If your doctor feels the Oesophageal Health Test isn’t right for you during your initial consultation, you’ll receive a full refund for the test, no questions asked.
Your results
Highly accurate
The Oesophageal Health Test has been shown to rule out Oesophageal cancer with 99.9% accuracy (Negative Predictive Value)9.
Clear
Gain meaningful insights about your health with easy-to-understand traffic light system to classify your risk.
Fast, high-quality results
Your sample is analysed in our lab and results are available in 2 to 4 weeks from when your blood is drawn - often quicker depending on your location.
Actionable
You and your doctor can use your report to understand if there is need for further diagnostic testing.
You have questions, we have answers
Easy to access, and even easier to understand.
What are the symptoms of oesophageal cancer?
Many people who have the early stages of oesophageal cancer do not have any symptoms, so it is often not picked up until the later stages.
When symptoms occur, they can include:
• pain or difficulty with swallowing or choking when you swallow
• getting food stuck in your throat or coming back up
• persistent heartburn or reflux
• pain in the upper part of your belly when you eat
• a persistent cough or hoarse voice.
What is the current oesophageal cancer testing process?
Currently, you need to have a specialist endoscopy-biopsy procedure to get a diagnosis. In this procedure, doctors pass a tube down your throat to examine your oesophagus and collect a sample of tissue for testing. This is invasive, can be costly, and it requires you to take time off work for the procedure.
Can a blood test detect oesophagus cancer?
The Oesophageal Health Test is a non-invasive blood test for the detection of oesophageal cancer. It identifies 4 biomarkers in the blood that are linked with this type of cancer, then combines this with age and body mass index (BMI) data to calculate a risk score. Clinical studies validating this test have reported high accuracy, with the test's ability to "rule out" Oesophageal Cancer with a 99.9% negative predictive value9.
Am I eligible for the test?
To be eligible, you must not have had a prior cancer diagnosis. You also need to have at least two risk factors for oesophageal adenocarcinoma, including:
• heartburn or chronic acid reflux (also known as gastroesophageal reflux disease or GORD)
• age > 50 years
• overweight (BMI > 25 kg/m²).
How do I do the test?
Follow these simple steps to take the Oesophageal Health Test.
1. Purchase the test online here.
2. Book your telehealth consult to get the pathology referral.
3. Take the referral to a collection centre and have your blood sample taken.
4. Wait for the referring doctor to contact you with results.
How much does it cost and can I get a Medicare rebate?
The Oesophageal Health Test costs $990 and is not currently funded under Medicare.
Can I get a refund if it turns out I’m not eligible?
Yes, we will give you a full refund if you purchase the test but are not eligible to go ahead with it.
How long until I get my results?
2 to 4 weeks depending on where you are located.
Are my results and personal details kept private?
We know health information is sensitive and take your privacy very seriously. Your test results are private and confidential – only you and your referring doctor have access to them.
We store your personal information on highly secure, encrypted servers and will never share your information with third parties without your permission. See our Privacy Policy for further information.
Do I need a doctor's referral?
You don’t need a referral from your usual GP to do the Oesophageal Health Test. One of our telehealth partner doctors can approve the pathology request for you. The cost of this consult is included in the purchase price.
References
- Bray F. et al, (2024) CA Cancer J Clin. 74(3), 229-263
- Shaheen N, et al. Barrett Esophagus, and Esophageal Cancer: Scientific Review. JAMA. 2002;287(15):1972–1981. doi:10.1001/jama.287.15.1972
- American Cancer Society. Esophageal Cancer Risk Factors. Last Revised: June 9, 2020. https://www.cancer.org/cancer/types/esophagus-cancer/causes-risks-prevention/risk-factors.html. Accessed 12 Dec 2024
- Dam et al., (2020) Ann. Transl. Med., 8(17): 1107
- Stawinski et al., (2023) Diagnostics (Basel). 13(2), 321.
- Visrodia et al., (2016) Gastro., 150(3), 599-607.e7
- https://www.proteomics.com.au/wp-content/uploads/240201-ASX-PIQ-Study-validates-biomarkers-for-oesophageal-cancer-blood-test.pdf
- Ibid.
- Sheahan, J., et al. A Clinical Validation of a Diagnostic Test for Esophageal Adenocarcinoma Based on a Novel Serum Glycoprotein Biomarker Panel: PromarkerEso. Proteomes 2025, 13, 23. https://doi.org/10.3390/proteomes13020023
Take your next step with confidence
Know your risk and your doctor can help you make your next healthcare decision with confidence.